Alveolar-arterial O₂ gradient

Required inputs

• FiO₂ (0.21-1.0)
• PaO₂ (mmHg)
• PaCO₂ (mmHg)
• Age (yrs)
• Atmospheric P (mmHg)

Equation or source

West JB. Respiratory Physiology, 11e.

Provenance and release status

Equation / algorithm

PAO₂ − PaO₂. Distinguishes hypoventilation from V/Q mismatch/shunt/diffusion.

Formula version

aa-grad-v1

Tool version

2.4.0

Clinical risk class

A. EDUCATIONAL CALCULATOR

Release status

Under clinical review

Source status

Direct primary source identifier not yet resolved

Clinical review status

Under clinical verification

Clinical review date

Clinical review date not yet documented

DOI / PMID / direct guideline identifier not yet documented.

Assumptions

• Entered values and units are accurate and apply to the population described by the cited source.
• The published equation or rule is being used without a patient-specific clinical adjustment.

Important limitations

• The result does not replace clinical assessment or establish a diagnosis.
• Performance outside the source population may differ.