Drug dosing
Aminoglycoside (once-daily) starting dose
Extended-interval gentamicin/tobramycin dosing for adults with broadly preserved renal function.
Required inputs
- Adjusted BW if obese, otherwise IBW (kg)
- CrCl (mL/min)
- Drug
Equation or source
Nicolau DP. AAC 1995;39:650. UKMI Hartford nomogram.
Provenance and release status
- Equation / algorithm
- Extended-interval gentamicin/tobramycin dosing for adults with broadly preserved renal function.
- Formula version
- aminoglycoside-od-v1
- Tool version
- 2.4.0
- Clinical risk class
- C. HIGH-RISK CLINICAL CALCULATOR
- Release status
- Temporarily unavailable
- Source status
- Direct primary source identifier not yet resolved
- Clinical review status
- Clinical verification incomplete; active calculation unavailable
- Clinical review date
- Clinical review date not yet documented
DOI / PMID / direct guideline identifier not yet documented.
Assumptions
- Entered values and units are accurate and apply to the population described by the cited source.
- The published equation or rule is being used without a patient-specific clinical adjustment.
Important limitations
- The result is a calculated estimate, not a prescription, treatment order, or diagnosis.
- Local protocols, the full clinical context, and the primary source must be checked before use.