Toxicology
Lithium toxicity — HD threshold
Screen for selected EXTRIP extracorporeal-treatment criteria in lithium toxicity; not a dialysis decision.
Required inputs
- Serum lithium (mEq/L)
- Acute / acute-on-chronic ingestion
- Significant CNS toxicity (seizures, ↓GCS, life-threatening dysrhythmia)
- Renal impairment (AKI / CKD limiting clearance)
- Unable to tolerate IV fluid resuscitation (e.g. heart failure)
Equation or source
Decker BS et al. EXTRIP workgroup. CJASN 2015;10:875-87.
Provenance and release status
- Equation / algorithm
- Screen for selected EXTRIP extracorporeal-treatment criteria in lithium toxicity; not a dialysis decision.
- Formula version
- extrip-li-2015-v1
- Tool version
- 2.4.0
- Clinical risk class
- C. HIGH-RISK CLINICAL CALCULATOR
- Release status
- Temporarily unavailable
- Source status
- Direct primary or authoritative source identifier resolved
- Clinical review status
- Clinical verification incomplete; active calculation unavailable
- Clinical review date
- Clinical review date not yet documented
Assumptions
- Entered values and units are accurate and apply to the population described by the cited source.
- The published equation or rule is being used without a patient-specific clinical adjustment.
Important limitations
- The result is a calculated estimate, not a prescription, treatment order, or diagnosis.
- Local protocols, the full clinical context, and the primary source must be checked before use.